| Mainrole |
Subrole |
Role ID |
| Unclassified |
Role category not yet assigned |
185 |
| Amino acid biosynthesis |
Aromatic amino acid family |
70 |
| Amino acid biosynthesis |
Aspartate family |
71 |
| Amino acid biosynthesis |
Glutamate family |
73 |
| Amino acid biosynthesis |
Pyruvate family |
74 |
| Amino acid biosynthesis |
Serine family |
75 |
| Amino acid biosynthesis |
Histidine family |
161 |
| Amino acid biosynthesis |
Other |
69 |
| Purines, pyrimidines, nucleosides, and nucleotides |
2'-Deoxyribonucleotide metabolism |
123 |
| Purines, pyrimidines, nucleosides, and nucleotides |
Nucleotide and nucleoside interconversions |
124 |
| Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
125 |
| Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
126 |
| Purines, pyrimidines, nucleosides, and nucleotides |
Salvage of nucleosides and nucleotides |
127 |
| Purines, pyrimidines, nucleosides, and nucleotides |
Sugar-nucleotide biosynthesis and conversions |
128 |
| Purines, pyrimidines, nucleosides, and nucleotides |
Other |
122 |
| Fatty acid and phospholipid metabolism |
Biosynthesis |
176 |
| Fatty acid and phospholipid metabolism |
Degradation |
177 |
| Fatty acid and phospholipid metabolism |
Other |
121 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
77 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Folic acid |
78 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
79 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Lipoate |
80 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
81 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Molybdopterin |
82 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
83 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridoxine |
84 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
85 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Glutathione and analogs |
86 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Thiamine |
162 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridine nucleotides |
163 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Chlorophyll and bacteriochlorphyll |
191 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Siderophores |
707 |
| Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
76 |
| Central intermediary metabolism |
Amino sugars |
100 |
| Central intermediary metabolism |
One-carbon metabolism |
698 |
| Central intermediary metabolism |
Phosphorus compounds |
103 |
| Central intermediary metabolism |
Polyamine biosynthesis |
104 |
| Central intermediary metabolism |
Sulfur metabolism |
106 |
| Central intermediary metabolism |
Nitrogen fixation |
179 |
| Central intermediary metabolism |
Nitrogen metabolism |
160 |
| Central intermediary metabolism |
Electron carrier regeneration |
709 |
| Central intermediary metabolism |
Other |
102 |
| Energy metabolism |
Aerobic |
108 |
| Energy metabolism |
Amino acids and amines |
109 |
| Energy metabolism |
Anaerobic |
110 |
| Energy metabolism |
ATP-proton motive force interconversion |
111 |
| Energy metabolism |
Electron transport |
112 |
| Energy metabolism |
Entner-Doudoroff |
113 |
| Energy metabolism |
Fermentation |
114 |
| Energy metabolism |
Glycolysis/gluconeogenesis |
116 |
| Energy metabolism |
Pentose phosphate pathway |
117 |
| Energy metabolism |
Pyruvate dehydrogenase |
118 |
| Energy metabolism |
Sugars |
119 |
| Energy metabolism |
TCA cycle |
120 |
| Energy metabolism |
Methanogenesis |
159 |
| Energy metabolism |
Biosynthesis and degradation of polysaccharides |
105 |
| Energy metabolism |
Photosynthesis |
164 |
| Energy metabolism |
Chemoautotrophy |
180 |
| Energy metabolism |
Other |
184 |
| Transport and binding proteins |
Amino acids, peptides and amines |
142 |
| Transport and binding proteins |
Anions |
143 |
| Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
144 |
| Transport and binding proteins |
Cations and iron carrying compounds |
145 |
| Transport and binding proteins |
Nucleosides, purines and pyrimidines |
146 |
| Transport and binding proteins |
Porins |
182 |
| Transport and binding proteins |
Other |
147 |
| Transport and binding proteins |
Unknown substrate |
141 |
| DNA metabolism |
DNA replication, recombination, and repair |
132 |
| DNA metabolism |
Restriction/modification |
183 |
| DNA metabolism |
Degradation of DNA |
131 |
| DNA metabolism |
Chromosome-associated proteins |
170 |
| DNA metabolism |
Other |
130 |
| Transcription |
Degradation of RNA |
134 |
| Transcription |
DNA-dependent RNA polymerase |
135 |
| Transcription |
Transcription factors |
165 |
| Transcription |
RNA processing |
166 |
| Transcription |
Other |
133 |
| Protein synthesis |
tRNA aminoacylation |
137 |
| Protein synthesis |
Ribosomal proteins: synthesis and modification |
158 |
| Protein synthesis |
tRNA and rRNA base modification |
168 |
| Protein synthesis |
Translation factors |
169 |
| Protein synthesis |
Other |
136 |
| Protein fate |
Protein and peptide secretion and trafficking |
97 |
| Protein fate |
Protein modification and repair |
140 |
| Protein fate |
Protein folding and stabilization |
95 |
| Protein fate |
Degradation of proteins, peptides, and glycopeptides |
138 |
| Protein fate |
Other |
189 |
| Regulatory functions |
DNA interactions |
261 |
| Regulatory functions |
RNA interactions |
262 |
| Regulatory functions |
Protein interactions |
263 |
| Regulatory functions |
Small molecule interactions |
264 |
| Regulatory functions |
Other |
129 |
| Signal transduction |
Two-component systems |
699 |
| Signal transduction |
PTS |
700 |
| Signal transduction |
Other |
710 |
| Cell envelope |
Surface structures |
91 |
| Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
89 |
| Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
90 |
| Cell envelope |
Other |
88 |
| Cellular processes |
Cell division |
93 |
| Cellular processes |
Chemotaxis and motility |
188 |
| Cellular processes |
Cell adhesion |
701 |
| Cellular processes |
Conjugation |
702 |
| Cellular processes |
Detoxification |
96 |
| Cellular processes |
DNA transformation |
98 |
| Cellular processes |
Sporulation and germination |
705 |
| Cellular processes |
Toxin production and resistance |
94 |
| Cellular processes |
Pathogenesis |
187 |
| Cellular processes |
Adaptations to atypical conditions |
149 |
| Cellular processes |
Biosynthesis of natural products |
706 |
| Cellular processes |
Other |
92 |
| Mobile and extrachromosomal element functions |
Plasmid functions |
186 |
| Mobile and extrachromosomal element functions |
Prophage functions |
152 |
| Mobile and extrachromosomal element functions |
Transposon functions |
154 |
| Mobile and extrachromosomal element functions |
Other |
708 |
| Unknown function |
Enzymes of unknown specificity |
703 |
| Unknown function |
General |
157 |
| Hypothetical proteins |
Conserved |
156 |
| Hypothetical proteins |
Domain |
704 |
| Disrupted reading frame |
|
270 |
